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PM 1080

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Drug Profile

PM 1080

Alternative Names: HS-20117; PM-1080

Latest Information Update: 01 Sep 2025

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At a glance

  • Originator Biotheus
  • Developer Biotheus; Jiangsu Hansoh Pharmaceutical
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II/III Non-small cell lung cancer
  • Phase I Solid tumours

Most Recent Events

  • 28 May 2025 Phase-II/III clinical trials in Non-small cell lung cancer (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, First-line therapy) in China (IV) (NCT06417008)
  • 09 May 2025 Jiangsu Hansoh Pharmaceutical plans a phase Ib trial in Solid tumours (Late-stage disease, Combination therapy, Metastatic disease) in China (IV) in May 2025 (NCT06963502)
  • 03 Feb 2025 Biotheus has been acquired by BioNTech

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