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PYC 003

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Drug Profile

PYC 003

Alternative Names: PYC-003

Latest Information Update: 10 Dec 2024

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At a glance

  • Originator PYC Therapeutics
  • Class Antisense oligonucleotides; Drug conjugates; Morpholines; Peptide drug conjugates
  • Mechanism of Action RNA interference; SHANK3 protein replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Polycystic kidney disease; Telomeric 22q13 Monosomy Syndrome

Most Recent Events

  • 03 Dec 2024 PYC Therapeutics plans a phase I trial for Polycystic kidney disease (IV, Infusion) in April 2025 (NCT06714006)
  • 13 Nov 2023 Preclinical trials in Polycystic kidney disease in Australia(unspecified route), prior to November 2023
  • 13 Nov 2023 PYC Therapeutics plans to file an IND application with the US FDA in USA for Polycystic kidney disease (PKD), in H2 2024

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