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AOH 1996

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Drug Profile

AOH 1996

Alternative Names: AOH-1996

Latest Information Update: 13 Jan 2025

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At a glance

  • Originator City of Hope National Medical Center
  • Developer City of Hope National Medical Center; RLL LLC
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proliferating cell nuclear antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours
  • Preclinical Acute myeloid leukaemia

Most Recent Events

  • 02 Jan 2025 City of Hope Medical Center plans a phase I/Ib for Acute myeloid leukaemia (Second-line therapy or greater, Combination therapy, Recurrent) in USA(PO) in August 2025 (NCT06763341)
  • 10 Dec 2024 Preclinical trials in Acute myeloid leukaemia in USA (unspecified route) prior to December 2024
  • 10 Dec 2024 Pharmacodynamics data from a preclinical study in Acute myeloid leukaemia released by City of Hope National Medical Center

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