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BBO 10203

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Drug Profile

BBO 10203

Alternative Names: BBO-10203; PI3K alpha:RAS breaker - BridgeBio Pharma

Latest Information Update: 03 Nov 2025

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At a glance

  • Originator BridgeBio Pharma
  • Developer BridgeBio Oncology Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Phosphatidylinositol 3 kinase alpha inhibitors; Ras signal transduction pathway inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 25 Oct 2025 Pharmacodynamics and adverse events data from a preclinical trial in Solid tumours released by BridgeBio Oncology Therapeutics
  • 15 Jun 2025 Pharmacodynamics data from a preclinical trial in Solid tumours released by BridgeBio Oncology Therapeutics
  • 10 Dec 2024 Pharmacodynamics data from preclinical studies in breast cancer presented at the 47th Annual San Antonio Breast Cancer Symposium (SABCS-2024)

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