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BBO 10203

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Drug Profile

BBO 10203

Alternative Names: BBO-10203; PI3K alpha:RAS breaker - BridgeBio Pharma

Latest Information Update: 17 Dec 2024

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At a glance

  • Originator BridgeBio Pharma
  • Developer BridgeBio Oncology Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Phosphatidylinositol 3 kinase alpha inhibitors; Ras signal transduction pathway inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 23 Oct 2024 Pharmacodynamics and adverse events data from preclinical trials in Solid tumours presented at 36th EORTC-NCI-AACR Symposium on molecular targets and cancer therapeutics (EORTC-NCI-AACR-2024)
  • 09 Oct 2024 Phase-I clinical trials in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Inoperable/Unresectable) in USA (PO) (NCT06625775)
  • 09 Oct 2024 Phase-I clinical trials in Solid tumours (Monotherapy, Late-stage disease, Metastatic disease, Inoperable/Unresectable) in USA (unspecified route) (NCT06625775)

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