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BBO 10203

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Drug Profile

BBO 10203

Alternative Names: BBO-10203; PI3K alpha:RAS breaker - BridgeBio Pharma

Latest Information Update: 14 Sep 2026

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At a glance

  • Originator BridgeBio Pharma
  • Developer BridgeBio Oncology Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Phosphatidylinositol 3 kinase alpha inhibitors; Ras signal transduction pathway inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours
  • Clinical Phase Unknown Adenocarcinoma; Colorectal cancer

Most Recent Events

  • 08 Sep 2026 Clinical trials in Adenocarcinoma (Combination therapy) (PO)
  • 08 Sep 2026 Clinical trials in Colorectal cancer (Combination therapy) (PO)
  • 22 Apr 2026 Pharmacodynamics data from a preclinical studies in Solid tumours presented at the 117th Annual Meeting of the American Association for Cancer Research (AACR 2026)

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