Drug Profile

BBO 10203

Alternative Names: BBO-10203; PI3K alpha:RAS breaker - BridgeBio Pharma

Latest Information Update: 12 Jan 2026

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At a glance

Originator BridgeBio Pharma
Developer BridgeBio Oncology Therapeutics
Class Antineoplastics; Small molecules
Mechanism of Action Phosphatidylinositol 3 kinase alpha inhibitors; Ras signal transduction pathway inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Solid tumours

Most Recent Events

07 Jan 2026 BridgeBio Pharma plans a combination trial later in 2026
07 Jan 2026 Efficacy, pharmacokinetics and adverse events data from a phase Ia/Ib trial in Solid tumours released by BridgeBio Pharma
11 Dec 2025 Pharmacodynamics data from a preclinical trial in Solid tumours released by BridgeBio Oncology Therapeutics

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