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TLC 6740

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Drug Profile

TLC 6740

Alternative Names: TLC-6740

Latest Information Update: 28 May 2026

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At a glance

  • Originator Gilead Sciences
  • Developer OrsoBio
  • Class Antihypercalcaemics; Hepatoprotectants; Obesity therapies
  • Mechanism of Action Mitochondrial oxidative phosphorylation uncouplers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Diabetes mellitus; Obesity
  • No development reported Lipodystrophy; Non-alcoholic steatohepatitis

Most Recent Events

  • 28 May 2026 No recent reports of development identified for phase-I development in Lipodystrophy(Combination therapy) in New Zealand (PO)
  • 28 May 2026 No recent reports of development identified for phase-I development in Non-alcoholic-steatohepatitis(Combination therapy) in New Zealand (PO)
  • 16 Dec 2025 Efficacy and adverse events data from a phase Ib/IIa trial in Obesity released by OrsoBio

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