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TLC 6740

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Drug Profile

TLC 6740

Alternative Names: TLC-6740

Latest Information Update: 25 Jun 2025

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At a glance

  • Originator Gilead Sciences
  • Developer OrsoBio
  • Class Antihypercalcaemics; Hepatoprotectants; Obesity therapies
  • Mechanism of Action Mitochondrial oxidative phosphorylation uncouplers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Diabetes mellitus; Lipodystrophy; Non-alcoholic steatohepatitis; Obesity

Most Recent Events

  • 20 Jun 2025 Pharmacodynamics data from a preclinical trial in Obesity released by OrsoBio
  • 09 Sep 2024 Pharmacodynamics data from a preclinical trial in Obesity presented at the 60th Annual Meeting of the European Association for the Study of Diabetes (EASD-2024)
  • 09 Sep 2024 Pharmacokinetics and pharmacodynamics data from a preclinical trial in Type 2 diabetes mellitus presented at the 60th Annual Meeting of the European Association for the Study of Diabetes (EASD-2024)

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