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ABBV 706

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Drug Profile

ABBV 706

Alternative Names: ABBV-706

Latest Information Update: 11 Sep 2025

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At a glance

  • Originator AbbVie
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours
  • Preclinical Neuroendocrine tumours; Small cell lung cancer

Most Recent Events

  • 04 Sep 2025 AbbVie plans a phase II/III (SEZanne) trial for Small cell lung cancer (First line therapy, Combination therapy) (IV, infusion) in December 2025 (NCT07155174)
  • 30 May 2025 Efficacy data from a phase I trial in Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
  • 30 May 2025 Efficacy and adverse event data from a phase I trial in Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)

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