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TLC 065

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Drug Profile

TLC 065

Alternative Names: TLC-065

Latest Information Update: 27 Dec 2023

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At a glance

  • Originator Mitobridge
  • Developer OrsoBio
  • Class Hepatoprotectants
  • Mechanism of Action Aminocarboxymuconate semialdehyde decarboxylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Fatty liver; Mitochondrial disorders; Non-alcoholic steatohepatitis

Most Recent Events

  • 10 Nov 2023 Preclinical trials in Non-alcoholic steatohepatitis in USA (unspecified route) before November 2023
  • 10 Nov 2023 Pharmacodynamics and adverse events data from a preclinical trial in Non-alcoholic steatohepatitis presented at the 74th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2023)
  • 02 Nov 2022 OrsoBio acquires ACMSD inhibitor program from Mitobridge

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