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SEL 018

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Drug Profile

SEL 018

Alternative Names: IdeZork (Xork); IgG protease - Cartesian Therapeutics; SEL-018; Xork; Xork IgG Protease

Latest Information Update: 03 Apr 2025

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At a glance

  • Originator Selecta Biosciences
  • Developer Cartesian Therapeutics
  • Class Peptide hydrolases
  • Mechanism of Action Proteolysis
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Glycogen storage disease type II

Most Recent Events

  • 13 Sep 2024 Selecta Biosciences terminates a licensing agreement with Genovis for the development of IgG proteases Xork
  • 06 Jun 2024 Cartesian Therapeutics terminates its licence of SEL 018 for development in Pompe disease
  • 23 Aug 2023 SEL 018 is available for licensing as of 17 Aug 2023

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