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AVS 100

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Drug Profile

AVS 100

Alternative Names: AVS-100

Latest Information Update: 14 Jun 2024

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At a glance

  • Originator Avstera Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action HDAC6 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Malignant melanoma
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Malignant melanoma; Solid tumours

Most Recent Events

  • 05 Apr 2024 Pharmacodynamics and adverse events data from a preclinical study in Malignant melanoma and Solid tumours presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)
  • 20 Dec 2023 US FDA approves IND application for AVS 100 in Solid tumours (Late-stage disease, Metastatic disease, Combination therapy) in USA (Avstera Therapeutics pipeline, December 2023)
  • 20 Dec 2023 Avstera Therapeutics plans a phase Ia/b trial for Solid tumours (Late-stage disease, Metastatic disease, Combination therapy) in USA (IV), in the first half of 2024 (Avstera Therapeutics pipeline December 2023)

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