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AMX 0114

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Drug Profile

AMX 0114

Alternative Names: AMX-0114

Latest Information Update: 22 May 2024

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At a glance

  • Originator Amylyx Pharmaceuticals
  • Class Antisense oligonucleotides
  • Mechanism of Action Calpain expression inhibitors; Gene silencing
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Amyotrophic lateral sclerosis; Neurodegenerative disorders

Most Recent Events

  • 09 May 2024 Amylyx Pharmaceuticals announces intention to submit an investigational new drug (IND) application to the US FDA for the clinical study of AMX 0114 in amyotrophic lateral sclerosis in the second half of 2024
  • 04 Apr 2024 Amylyx Pharmaceuticals plans a clinical trial for Amyotrophic lateral sclerosis in the second half of 2024
  • 11 Mar 2024 Interim pharmacodynamics data from a preclinical studies in Amyotrophic lateral sclerosis released by Amylyx Pharmaceuticals

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