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Imapextide - MBX Biosciences

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Drug Profile

Imapextide - MBX Biosciences

Alternative Names: MBX-1416

Latest Information Update: 26 Sep 2025

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At a glance

  • Originator MBX Biosciences
  • Class Antihypoglycaemics; Peptide hormones
  • Mechanism of Action Glucagon-like peptide-1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hypoglycaemia

Most Recent Events

  • 26 Sep 2025 Phase-II clinical trials in Hypoglycaemia in USA (SC) (Prior to September 2025) (NCT07029412) (MBX Biosciences pipeline, September 2025)
  • 07 Aug 2025 MBX Biosciences plans a phase IIa trial for Hypoglycaemia in the US, in the third quarter of 2025 (SC, Injection) (NCT07029412)
  • 20 Jun 2025 Pharmacokinetics and pharmacodynamics data from a preclinical trial presented at the 85th Annual Scientific Sessions of the American Diabetes Association (ADA-2025)

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