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DSP 0378

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Drug Profile

DSP 0378

Alternative Names: DSP-0378

Latest Information Update: 10 Oct 2025

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At a glance

  • Originator Sumitomo Pharma
  • Class Antiepileptic drugs; Small molecules
  • Mechanism of Action GABA A receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Brain disorders
  • Preclinical Progressive myoclonic epilepsies
  • Discontinued Dravet syndrome; Lennox-Gastaut syndrome

Most Recent Events

  • 10 Oct 2025 Preclinical trials in Progressive-myoclonic-epilepsies in Japan (PO), prior to October 2025 (Sumitomo Pharma pipeline, October 2025)
  • 09 Oct 2025 Phase-I clinical trials in Brain disorders in Japan (PO), prior to October 2025 (Sumitomo Pharma pipeline, October 2025)
  • 08 Oct 2025 Discontinued - Phase-I for Dravet syndrome (In children, In infants, Treatment-resistant) in Japan (PO)

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