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PRO 1286

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Drug Profile

PRO 1286

Alternative Names: GEN 1286; PRO-1286

Latest Information Update: 20 Nov 2024

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At a glance

  • Originator ProfoundBio
  • Developer Genmab
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 14 Nov 2024 Genmab plans a phase I/II trial for Solid tumours (Late-stage disease, Metastatic disease, Inoperable/Unresectable, Second-line therapy or greater) (Parenteral) in November 2024 (NCT06685068)
  • 13 Nov 2024 Phase-I/II clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Inoperable/Unresectable, Recurrent, Second-line therapy or greater) in USA (Parenteral) (NCT06685068)
  • 21 May 2024 ProfoundBio has been acquired by Genmab

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