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AUM 302

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Drug Profile

AUM 302

Alternative Names: AUM-302; IBL 302

Latest Information Update: 09 Jun 2023

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At a glance

  • Originator Spanish National Cancer Research Centre
  • Developer AUM Biosciences; Inflection Biosciences; Royal College of Surgeons
  • Class 2 ring heterocyclic compounds; Antineoplastics; Aza compounds; Ethers; Fluorobenzenes; Ketones; Pyridines; Pyrimidines; Small molecules; Sulfonamides; Thiophenes
  • Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors; MTOR protein inhibitors; PIM3 protein inhibitors; Proto oncogene protein c pim 1 inhibitors; Proto-oncogene protein pim-2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Neuroblastoma
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Acute myeloid leukaemia; Breast cancer; Lung cancer; Neuroblastoma; Prostate cancer

Most Recent Events

  • 09 Jun 2023 Chemical structure information added
  • 06 May 2023 Pharmacodynamics data from a preclinical trial in Pancreatic cancer presented at the Digestive Disease Week 2023 (DDW-2023)
  • 05 Jan 2023 AUM 302 receives Rare Paediatric Disease designation from the US FDA for treatment of Neuroblastoma

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