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HS 135

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Drug Profile

HS 135

Alternative Names: HS-135

Latest Information Update: 09 Jun 2025

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At a glance

  • Originator 35Pharma
  • Class Antihypertensives; Heart failure therapies; Recombinant fusion proteins
  • Mechanism of Action ACVR1 protein inhibitors; Myostatin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Pulmonary arterial hypertension
  • Phase I Heart failure

Most Recent Events

  • 30 Mar 2025 35Pharma terminates phase I/II trial in Pulmonary arterial hypertension in Canada and Germany (SC) (NCT06493461)
  • 23 Jan 2025 Phase-I clinical trials in Pulmonary arterial hypertension in USA (SC) (NCT06581159)
  • 23 Jan 2025 Phase-I clinical trials in Heart failure in USA (SC) (NCT06581159)

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