HK 660S
Alternative Names: Beta-Lapachone; HK-660-SLatest Information Update: 22 May 2025
At a glance
- Originator CUROME BIOSCIENCES
- Class Anti-inflammatories; Antifibrotics; Antineoplastics; Eye disorder therapies; Naphthoquinones; Obesity therapies; Small molecules
- Mechanism of Action NQO1 modulators
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Primary sclerosing cholangitis
Most Recent Events
- 16 May 2025 CuromeBiosciences plans a phase II trial for Primary sclerosing cholangitis in August 2025 (PO) (NCT06975150)
- 15 Nov 2024 Efficacy data from a phase II trial in Primary sclerosing cholangitis presented at the The Liver Meeting 2024: 75th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2024)
- 05 Jun 2024 Efficacy, Adverse events and pharmacodynamics data from a phase II trial in Primary sclerosing cholangitis presented at the European Association for the Study of the Liver Congress 2024 (EASL-2024)