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HDT 321

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Drug Profile

HDT 321

Alternative Names: HDT-321

Latest Information Update: 30 Sep 2025

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At a glance

  • Originator HDT Bio; University of Texas Medical Branch
  • Class RNA vaccines; Viral vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Crimean-Congo haemorrhagic fever virus infections

Most Recent Events

  • 19 Sep 2025 National Institutes of Health's National Institute of Allergy and Infectious Diseases establishes CRADA with University of Texas Medical Branch for the development of HDT 321 in Crimean-Congo haemorrhagic fever virus infections
  • 19 Sep 2025 The US FDA approves an IND application for HDT 321 in Crimean-Congo haemorrhagic fever virus infections
  • 10 Jul 2025 Phase-I clinical trials in Crimean-Congo haemorrhagic fever virus infections (Prevention) in USA (IM) (NCT06799013)

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