VGA 039
Alternative Names: VGA-039Latest Information Update: 10 Feb 2026
At a glance
- Originator Vega Therapeutics
- Class Antihaemorrhagics; Coagulants; Monoclonal antibodies
- Mechanism of Action Protein S inhibitors
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Orphan Drug Status
Yes - Von Willebrand disease
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III Von Willebrand disease
Most Recent Events
- 10 Feb 2026 Pharmacodynamics data from preclinical trial in Von Willebrand disease presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2025)
- 06 Dec 2025 Efficacy and adverse events data from a phase I/II trial in Von Willebrand disease presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2025)
- 06 Dec 2025 Efficacy and adverse event data from phase III trial in Von Willebrand disease released by Star Therapeutics