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ALN KHK

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Drug Profile

ALN KHK

Alternative Names: ALN-KHK

Latest Information Update: 15 Dec 2023

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At a glance

  • Originator Alnylam Pharmaceuticals
  • Class Antihyperglycaemics; Small interfering RNA
  • Mechanism of Action Fructokinases expression modulators; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Type 2 diabetes mellitus

Most Recent Events

  • 13 Dec 2023 Safety, pharmacokinetics and pharmacodynamics data from a phase I/II trial in Type 2 diabetes mellitus released by Alnylam Pharmaceuticals
  • 10 Mar 2023 Phase-I/II clinical trials in Type 2 diabetes mellitus in Canada (SC, Injection) (NCT05761301)
  • 22 Dec 2022 Alnylam Pharmaceuticals submits a clinical trial authorization application with the Health Canada in Canada for Type 2 diabetes mellitus

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