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YL 202

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Drug Profile

YL 202

Alternative Names: BNT-326; YL-202

Latest Information Update: 12 Aug 2024

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At a glance

  • Originator MediLink Therapeutics
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Solid tumours
  • Phase I HER2 negative breast cancer; Non-small cell lung cancer

Most Recent Events

  • 17 Jun 2024 US FDA places partial clinical hold on a phase I trial in Non-small cell lung cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA and China (IV) (NCT05653752)
  • 03 Jun 2024 MediLink Therapeutics plans a phase II trial for Breast cancer (Metastatic disease, Late-stage disease, Inoperable/Unresectable) in China (IV, Infusion) (NCT06439771)
  • 31 May 2024 Efficacy, adverse events and pharmacokinetics data from a phase-I trial in Non-small Cell Lung Cancer and Breast Cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)

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