Drug Profile

EDG 7500

Alternative Names: EDG-7500

Latest Information Update: 11 Mar 2026

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At a glance

Originator Edgewise Therapeutics
Class Cardiovascular therapies; Heart failure therapies; Small molecules; Urologics
Mechanism of Action Sarcomere modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Hypertrophic cardiomyopathy
Phase I Kidney disorders
Preclinical Cardiovascular disorders

Most Recent Events

06 Mar 2026 dgewise Therapeutics plans a phase I trial for Healthy volunteers in the US in March 2026 (PO) (NCT07456059)
26 Jan 2026 Edgewise Therapeutics initiates enrolment in a phase I pharmacokinetics trial for in the USA (NCT07324616)
07 Jan 2026 Edgewise Therapeutics plans a phase I trial for Liver disorders in USA in January 2026 (PO) (NCT07324616)

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