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CRD 3874

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Drug Profile

CRD 3874

Alternative Names: CRD-3874; CRD3874-SI

Latest Information Update: 17 Jun 2025

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At a glance

  • Originator Curadev Pharma
  • Developer Curadev Pharma; University of Maryland, Baltimore
  • Class Antineoplastics; Small molecules
  • Mechanism of Action STING1 protein stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia; Merkel cell carcinoma; Sarcoma
  • Preclinical Solid tumours

Most Recent Events

  • 10 Jun 2025 Curadev Pharma and Memorial Sloan Kettering Cancer Center (MSK) expand there collaboration through the MSK Therapeutics Accelerator program to advance the development of CRD3874 SI
  • 25 Apr 2025 Pharmacodynamics data from a preclinical trial in Acute myeloid leukaemia presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 26 Aug 2024 Phase-I clinical trials in Acute myeloid leukaemia in USA (IV) (NCT06626633)

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