APG 808
Alternative Names: APG-808; PR-001 - Paragon TherapeuticsLatest Information Update: 14 Apr 2026
At a glance
- Originator Apogee Therapeutics; Paragon Therapeutics
- Developer Apogee Therapeutics
- Class Anti-inflammatories; Antiasthmatics; Monoclonal antibodies
- Mechanism of Action Interleukin 4 receptor alpha subunit antagonists
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Asthma; Chronic obstructive pulmonary disease; Inflammation
Most Recent Events
- 06 Nov 2025 Pharmacokinetics, adverse events and pharmacodynamics data from a phase I trial (In volunteers) presented at the 2025 Annual Scientific Meeting of the American College of Allergy, Asthma & Immunology (ACAAI-2025)
- 12 May 2025 Efficacy and adverse event data from phase Ib trial in Asthma released by Apogee Therapeutics
- 12 May 2025 Apogee Therapeutics initiates a phase Ib trial for Asthma, prior to May 2025