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APG 808

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Drug Profile

APG 808

Alternative Names: APG-808; PR-001 - Paragon Therapeutics

Latest Information Update: 19 May 2025

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At a glance

  • Originator Apogee Therapeutics; Paragon Therapeutics
  • Developer Apogee Therapeutics
  • Class Anti-inflammatories; Antiasthmatics; Monoclonal antibodies
  • Mechanism of Action Interleukin 4 receptor alpha subunit antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Asthma; Chronic obstructive pulmonary disease; Inflammation

Most Recent Events

  • 12 May 2025 Efficacy and adverse event data from phase Ib trial in Asthma released by Apogee Therapeutics
  • 12 May 2025 Apogee Therapeutics initiates a phase Ib trial for Asthma, prior to May 2025
  • 02 Dec 2024 Phase-I clinical trials in Asthma (SC)

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