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SION 719

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Drug Profile

SION 719

Alternative Names: SION-719

Latest Information Update: 11 Nov 2025

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At a glance

  • Originator Sionna Therapeutics
  • Class Antifibrotics; Small molecules
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cystic fibrosis

Most Recent Events

  • 05 Nov 2025 Sionna Therapeutics completes a drug-drug interaction study with midazolam
  • 30 Oct 2025 Phase-II clinical trials in Cystic fibrosis (Adjunctive treatment) in USA (PO) (NCT07108153)
  • 06 Aug 2025 Sionna Therapeutics plans a phase IIa trial for Cystic fibrosis (Adjunctive treatment) in USA and Australia in October 2025 (NCT07108153)

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