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SION 719

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Drug Profile

SION 719

Alternative Names: SION-719

Latest Information Update: 22 Aug 2025

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At a glance

  • Originator Sionna Therapeutics
  • Class Antifibrotics; Small molecules
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Cystic fibrosis

Most Recent Events

  • 06 Aug 2025 Sionna Therapeutics plans a phase IIa trial for Cystic fibrosis (Adjunctive treatment) in USA and Australia in October 2025 (NCT07108153)
  • 06 Jun 2025 Sionna Therapeutics completes a phase I trial in Cystic fibrosis (In volunteers) in Australia (unspecified route)
  • 06 Jun 2025 Pharmacodynamics data from a preclinical study in Cystic fibrosis released in Sionna Therapeutics

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