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FPI 2068

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Drug Profile

FPI 2068

Alternative Names: [225Ac]-FPI-2068; actinium-225 FPI-2068; AZD-2068; FPI-2068

Latest Information Update: 21 Aug 2026

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At a glance

  • Originator AstraZeneca; Fusion Pharmaceuticals
  • Class Antineoplastics; Bispecific antibodies; Drug conjugates; Immunoconjugates; Radioisotopes; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 27 Jul 2026 Discontinued - Phase-I for Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Recurrent) in USA due to pharmacokinetics/pharmacodynamics (IV) (AstraZeneca pipeline, July 2026)
  • 01 Jul 2024 Phase-I clinical trials in Solid tumours (Inoperable/Unresectable, Metastatic disease, Late-stage disease, Recurrent) in USA (IV) (NCT06147037)
  • 04 Jun 2024 Fusion Pharmaceuticals has been acquired by AstraZeneca

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