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AST 201

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Drug Profile

AST 201

Alternative Names: pUMVC3-hIGFBP-2 multi-epitope plasmid DNA vaccine; AST-201; pUMVC3-hIGFBP-2

Latest Information Update: 16 Jun 2024

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At a glance

  • Originator Aston Science
  • Developer University of Washington
  • Class Antineoplastics; Cancer vaccines; DNA vaccines; Immunotherapies; Vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Ovarian cancer

Most Recent Events

  • 05 Apr 2024 Pharmacodynamics data from preclinical studies in Ovarian cancer presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)
  • 12 Sep 2023 US FDA approves phase II IND application for AST 201 in Ovarian cancer
  • 06 Apr 2023 Aston Science plans the phase II Cornerstone4 trial for Ovarian cancer (Late-staged disease, Second-line therapy or greater) in USA (NCT05794659)

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