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Research programme: mRNA-based therapeutics - CytomX Therapeutics/Moderna

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Drug Profile

Research programme: mRNA-based therapeutics - CytomX Therapeutics/Moderna

Alternative Names: mRNA encoded masked IL-12 - CytomX Therapeutics/Moderna; mRNA-based therapeutics; mRNA-based therapeutics - CytomX Therapeutics/Moderna

Latest Information Update: 12 May 2026

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At a glance

  • Originator CytomX Therapeutics; Moderna Therapeutics
  • Class Antineoplastics; RNA
  • Mechanism of Action Interleukin 12 replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 31 Mar 2026 CytomX Therapeutics paused development of mRNA based therapeutics in Cancer in USA
  • 07 May 2025 Preclinical trials in Cancer in USA (Parenteral)
  • 28 Apr 2025 Pharmacodynamics data from preclinical studies in Cancer released by CytomX Therapeutics

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