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TT 00973

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Drug Profile

TT 00973

Alternative Names: TT-00973; TT-00973-MS

Latest Information Update: 04 Sep 2025

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At a glance

  • Originator TransThera Biosciences
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Axl receptor tyrosine kinase inhibitors; Fms-like tyrosine kinase 3 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours
  • Preclinical Acute myeloid leukaemia

Most Recent Events

  • 30 May 2025 Phase-I clinical trials in Solid tumours (Late-stage disease; Second-line therapy or greater) in China (PO) prior to May 2025 (NCT05673538)
  • 30 May 2025 Efficacy, pharmacodynamic and adverse events data from a phase I trial in Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
  • 12 Jan 2023 Preclinical trials in Acute myeloid leukaemia in China (PO) before January 2023 (TransThera Biosciences pipeline, January 2023)

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