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Cagrilintide/semaglutide - Novo Nordisk

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Drug Profile

Cagrilintide/semaglutide - Novo Nordisk

Alternative Names: CagriSema; NN-9388; Semaglutide/Cagrilintide - Novo Nordisk

Latest Information Update: 02 Jan 2026

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At a glance

  • Originator Novo Nordisk
  • Class Antihyperglycaemics; Glucagon-like peptides; Hepatoprotectants; Obesity therapies; Urologics; Vascular disorder therapies
  • Mechanism of Action Amylin receptor agonists; Glucagon-like peptide-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Preregistration Obesity
  • Phase III Type 2 diabetes mellitus
  • Phase II Alcoholic liver disorders; Diabetic neuropathies

Most Recent Events

  • 18 Dec 2025 Preregistration for Obesity in USA (SC)
  • 18 Dec 2025 USFDA is expected to review the NDA for CagriSema in 2026
  • 15 Dec 2025 Novo Nordisk A/S plans a phase III trial for the treatment of Type 2 Diabetes in US, Argentina, Brazil, and Israel (SC), in August 2026 (NCT07282613)

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