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LEO 158968

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Drug Profile

LEO 158968

Alternative Names: LEO-158968; LP-0189

Latest Information Update: 28 Mar 2026

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At a glance

  • Originator LEO Pharma; MorphoSys
  • Developer LEO Pharma
  • Class Analgesics; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Interleukin-1 receptor accessory protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Pain
  • No development reported Skin disorders

Most Recent Events

  • 28 Mar 2026 No recent reports of development identified for phase-I development in Skin-disorders(In volunteers) in Netherlands (IV, Injection)
  • 28 Mar 2026 No recent reports of development identified for phase-I development in Skin-disorders(In volunteers) in Netherlands (SC, Injection)
  • 08 Sep 2025 LEO Pharma completes a phase I trial in Pain in Netherlands, France, United Kingdom (SC) (NCT06444867)

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