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FL 501

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Drug Profile

FL 501

Alternative Names: FL-501

Latest Information Update: 23 May 2025

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At a glance

  • Originator Adimab; Flame Biosciences
  • Developer Leap Therapeutics
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Growth differentiation factor 15 inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cachexia

Most Recent Events

  • 13 May 2025 Pharmacodynamics and adverse events data from preclinical trials in Cachexia released by Leap Therapeutics
  • 25 Apr 2025 Pharmacodynamics data from preclinical studies in Cachexia presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 25 Apr 2025 Pharmacokinetics and pharmacodynamics data from preclinical trials in Cachexia released by Leap Therapeutics

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