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KN 5501

Drug Profile

KN 5501

Alternative Names: Anti-CD19 CAR NK cells; KN-5501

Latest Information Update: 03 Apr 2024

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At a glance

  • Originator Nanjing Enricnk Biotech; Rui Therapeutics
  • Class Antineoplastics; CAR-NK cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; Natural killer cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Diffuse large B cell lymphoma
  • Phase 0 Autoimmune disorders

Most Recent Events

  • 30 Mar 2024 Rui Therapeutics plans a phase 0 trial for Immune thrombocytopenia (Treatment-experienced) and Systemic lupus erythematosus in March 2024 (Infusion, Injection) (NCT06337474)
  • 13 Mar 2024 Phase-0 clinical trials in Autoimmune disorders (In adults, In the elderly) in China (Parenteral) (NCT06318533)
  • 01 Mar 2023 Phase-I clinical trials in Diffuse large B cell lymphoma (Second-line therapy or greater, In adults, In the elderly) in China (Parenteral) (NCT05673447)
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