Drug Profile

TTI 109

Alternative Names: TTI-109

Latest Information Update: 07 Aug 2026

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At a glance

Originator Tvardi Therapeutics
Class Antifibrotics; Antineoplastics; Small molecules
Mechanism of Action STAT3 transcription factor inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Cancer; Fibrosis

Most Recent Events

30 Jul 2026 Tvardi Therapeutics files an IND application for ulcerative colitis prior to July 2026
30 Jul 2026 Tvardi Therapeutics plans a clinical trial for Ulcerative colitis in 2027
07 Jul 2026 Tvardi Therpeutics completes a phase I trial in Cancer (In volunteers) and Fibrosis (In volunteers) in unknown location (PO)

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