Drug Profile

VP 301

Alternative Names: CD38 x ICAM-1 bsAb - Virtuoso Therapeutics; VP-301

Latest Information Update: 10 Oct 2025

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At a glance

Originator Virtuoso Therapeutics
Class Antineoplastics; Bispecific antibodies; Immunotherapies
Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

10 Oct 2025 Phase I development in Multiple myeloma is underway in USA (IV) (Virtuoso Therapeutics pipeline, October 2025)
19 Jun 2023 Virtuoso terminates a phase-I clinical trial in Solid tumours, Multiple myeloma (Second-line therapy or greater) in USA (IV) due to sponsor decision (NCT05698888)
29 Nov 2022 Phase-I clinical trials in Multiple myeloma (Second-line therapy or greater) in USA (IV) (NCT05698888)

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