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BIS 2

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Drug Profile

BIS 2

Alternative Names: BIS-2; LB-4330

Latest Information Update: 25 Jun 2024

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At a glance

  • Originator L and L Biopharma
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours
  • Phase I Gastric cancer; Pancreatic cancer

Most Recent Events

  • 21 Jun 2024 L and L Biopharma plans a phase I/II TRIGGERCD8 trial for Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (IV) in June 2024(NCT06468358)
  • 19 Jun 2024 Phase-I/II clinical trials in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (IV) (NCT06468358)
  • 31 May 2024 Efficacy, adverse event and pharmacokinetic data from a phase I trial in Solid tumours presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)

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