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SPL 5B

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Drug Profile

SPL 5B

Alternative Names: SPL-5-B

Latest Information Update: 08 Sep 2025

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At a glance

  • Originator SpliSense
  • Class Antifibrotics; Antisense oligonucleotides
  • Mechanism of Action Mucin 5B expression modulators; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Idiopathic pulmonary fibrosis

Most Recent Events

  • 03 Sep 2025 SpliSense plans a clinical trial for Idiopathic pulmonary fibrosis (Inhalation) in early 2026
  • 08 Feb 2023 Preclinical trials in Idiopathic pulmonary fibrosis in Israel (Inhalation) (SpliSense pipeline, February 2023)

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