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Desmethyl cariprazine prodrug - Abbvie

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Drug Profile

Desmethyl cariprazine prodrug - Abbvie

Alternative Names: ABBV-932; RGH-932

Latest Information Update: 28 Oct 2025

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At a glance

  • Originator Gedeon Richter
  • Developer AbbVie; Gedeon Richter
  • Class Antidepressants; Anxiolytics; Mood stabilisers; Small molecules
  • Mechanism of Action Dopamine D2 receptor partial agonists; Dopamine D3 receptor partial agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Bipolar depression; Bipolar disorders; Generalised anxiety disorder
  • Phase I Unspecified

Most Recent Events

  • 30 Sep 2025 Phase-II clinical trials in Bipolar disorders in USA (PO) (NCT07220460)
  • 21 Aug 2025 AbbVie initiates a phase-I pharmacokinetics trial (In volunteers) in China (PO, Capsule) (NCT07024797)
  • 15 Jul 2025 AbbVie initiates a phase I trial (In volunteers, Combination therapy) (PO) (NCT07071532)

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