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GLPG 5301

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Drug Profile

GLPG 5301

Alternative Names: GLPG-5301

Latest Information Update: 04 Mar 2026

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At a glance

  • Originator Galapagos NV
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Multiple myeloma

Most Recent Events

  • 24 Feb 2026 Galapagos terminates a phase I/II PAPILIO-1 trial for Multiple myeloma (Second-line therapy or greater) in Europe (Parenteral) as the company decides to wind down cell therapy development
  • 21 Oct 2025 Galapagos NV plans to wind down cell therapy therapeutics as per business strategy
  • 30 Oct 2024 Galapagos resumes enrolment in the phase I/II PAPILIO-1 trial for Multiple myeloma in Europe

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