Drug Profile

Metabolically armed anti-CD19 chimeric antigen receptor T cell therapy - Leman Biotech

Alternative Names: Anti-CD19 chimeric antigen receptor T cell therapy - Leman Biotech; Meta10-19 - Leman Biotech

Latest Information Update: 21 Feb 2025

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At a glance

Originator Leman Biotech
Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

Phase I Diffuse large B cell lymphoma; Non-Hodgkin's lymphoma; Precursor B-cell lymphoblastic leukaemia-lymphoma; Systemic lupus erythematosus

07 Dec 2024 Efficacy, pharmacokinetics and adverse events data from a phase I trial in Diffuse large B-cell lymphoma presented at the 66th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2024)
07 Dec 2024 Efficacy and adverse events data from a phase I trial in Non Hodgkin's lymphoma and Precurssor B cell lymphoblastic leukemia-lymphoma presented at the 66^th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2024)
01 Dec 2024 Phase-I clinical trials in Systemic lupus erythematosus in China (IV) (NCT06711146)

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