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PM 359

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Drug Profile

PM 359

Alternative Names: PM-359

Latest Information Update: 26 Aug 2024

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At a glance

  • Originator Prime Medicine
  • Class Gene therapies; Immunotherapies
  • Mechanism of Action Gene transference; Neutrophil cytosolic factor 1 replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chronic granulomatous disease
  • New Molecular Entity No

Highest Development Phases

  • Preclinical Chronic granulomatous disease

Most Recent Events

  • 19 Aug 2024 Prime Medicine plans a phase I/II trial for Chronic granulomatous disease (Treatment experienced) in September 2024 (IV)(NCT06559176)
  • 08 May 2024 Pharmacodynamics data from a preclinical trial in chronic granulomatous disease released by Prime Medicine
  • 29 Apr 2024 The US FDA approves IND application for PM 359 in Chronic granulomatous disease

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