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JS 015

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Drug Profile

JS 015

Alternative Names: JS-015

Latest Information Update: 28 Aug 2026

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At a glance

  • Originator Shanghai Junshi Biosciences
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; DKK1 protein inhibitors; Myeloid-derived suppressor cell inhibitors; Natural killer cell stimulants; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 28 Aug 2026 Shanghai Junshi Bioscience completes a Phase I/II trial in Solid tumours (Combination therapy, Late-stage disease, Inoperable/Unresectable, Metastatic disease) in China (IV) (NCT06139211)
  • 28 Apr 2026 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease) in China (IV, Infusion)
  • 17 Apr 2024 Fudan University plans a phase I/II FD-IMPACT trial for Pancreatic Cancer in China (IV) (NCT06370754)

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