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EXS 74539

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Drug Profile

EXS 74539

Alternative Names: '539; EXS-74539; REC-4539

Latest Information Update: 18 Mar 2025

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At a glance

  • Originator Bristol-Myers Squibb; Exscientia
  • Developer Recursion Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Lysine specific demethylase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Acute myeloid leukaemia; Small cell lung cancer

Most Recent Events

  • 07 Jan 2025 US FDA approves IND application for EXS 74539 in olid tumours including small cell lung cancer
  • 20 Nov 2024 Exscientia has been acquired and merged into Recursion Pharmaceuticals
  • 09 Oct 2024 Pharmacodynamics data from a preclinical trial in Acute myeloid leukaemia released by Exscientia

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