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GS 6791

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Drug Profile

GS 6791

Alternative Names: GS-6791; NX‑0479

Latest Information Update: 23 Sep 2025

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At a glance

  • Originator Nurix
  • Developer Gilead Sciences; Nurix
  • Class Anti-inflammatories; Antirheumatics; Skin disorder therapies; Small molecules
  • Mechanism of Action IRAK4 protein degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Inflammation
  • Preclinical Atopic dermatitis; Rheumatoid arthritis

Most Recent Events

  • 17 Sep 2025 Preclinical trials in Atopic dermatitis in USA (PO)
  • 17 Sep 2025 Pharmacodynamics data from preclinical studies released by Nurix Therapeutics
  • 27 Aug 2025 Phase-I clinical trials in Inflammation in USA (PO) (Gilead Sciences pipeline, August 2025)

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