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XNW 27011

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Drug Profile

XNW 27011

Alternative Names: ASP-546C; XNW 27; XNW-27011

Latest Information Update: 26 Sep 2025

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At a glance

  • Originator Evopoint Biosciences
  • Developer Astellas Pharma; Evopoint Biosciences
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Adenocarcinoma
  • Phase I/II Solid tumours

Most Recent Events

  • 26 Sep 2025 Efficacy and adverse event data from a phase I/II trial in Solid tumours presented at the presented at the 61st Annual Meeting of the American Society of Clinical Oncology 2025 (ASCO-2025)
  • 30 Mar 2025 Phase-III clinical trials in Adenocarcinoma (Inoperable/Unresectable, Late-stage disease) in China (Parenteral)
  • 30 Mar 2025 Astellas plans a global phase I/II trial

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