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XNW 27011

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Drug Profile

XNW 27011

Alternative Names: ASP-546C; XNW 27; XNW-27011

Latest Information Update: 20 Aug 2026

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At a glance

  • Originator Evopoint Biosciences
  • Developer Astellas Pharma; Evopoint Biosciences
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Adenocarcinoma
  • Phase I/II Solid tumours

Most Recent Events

  • 02 Jun 2026 Efficacy data from phase I/II trial in Solid tumours presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (AACR-2026)
  • 02 Jun 2026 Efficacy and adverse events data from a G/GEJA portion of a phase I/II trial in Solid tumours presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (AACR-2026)
  • 29 May 2026 Pharmacokinetics, efficacy and adverse events data from a G/GEJA portion of a phase I/II trial in Solid tumours presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (AACR-2026)

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