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MT 125

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Drug Profile

MT 125

Alternative Names: MT-125

Latest Information Update: 31 Oct 2025

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At a glance

  • Originator Myosin Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Myosin heavy chain modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioblastoma
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Glioblastoma

Most Recent Events

  • 22 Oct 2025 MT 125 receives Fast Track designation for Glioblastoma in USA
  • 22 Oct 2025 The US FDA clears IND for MT 125 for the initiation of a phase I/II trial, prior to October 2025
  • 30 Sep 2025 Myosin Therapeutics plans a phase I STAR-GBM trial for Glioblastoma (first-line therapy) in USA in November 2025 (NCT07185880) .

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