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DNL 622

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Drug Profile

DNL 622

Alternative Names: DNL-622; ETV-IDUA - Denali Therapeutics; ETV:Alpha-L-Iduronidase

Latest Information Update: 25 Apr 2023

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At a glance

  • Originator Denali Therapeutics Inc
  • Class Enzymes; Recombinant fusion proteins
  • Mechanism of Action Iduronidase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Mucopolysaccharidosis I

Most Recent Events

  • 27 Mar 2023 Preclinical trials in Mucopolysaccharidosis I in USA (Parenteral), prior to March 2023 (Denali Therapeutics pipeline, March 2023)

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