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JAB 30300

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Drug Profile

JAB 30300

Alternative Names: JAB-30300; JAB-30355; P53 Y220C activator - Jacobio Pharmaceuticals

Latest Information Update: 06 Nov 2024

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At a glance

  • Originator Jacobio Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Tumour suppressor protein p53 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 24 Jul 2024 Phase-I/II clinical trials in Solid tumours (Late-stage disease, Second-line therapy or greater) in China (PO) (NCT06386146)
  • 24 Jul 2024 Phase-I/II clinical trials in Solid tumours (Late-stage disease, Second-line therapy or greater) in USA (PO) (NCT06386146)
  • 19 Jun 2024 Pharmacodynamics, pharmacokinetics and adverse event data from a preclinical trial in Solid tumours presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)

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